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/Chemokines and Cytokines (10)
/Monocyte Chemotactic Protein-1 (65-76) (human) trifluoroacetate salt
Product details
Cat#: 125P04
Three Letter Code: H-Asp-His-Leu-Asp-Lys-Gln-Thr-Gln-Thr-Pro-Lys-Thr-OH trifluoroacetate salt
One Letter Code: DHLDKQTQTPKT
Synonyms: HC11 (65-76) (human), MCP-1 (65-76) (human), MCAF (65-76) (human), Small Inducible Cytokine A2 (65-76) (human)
Molecular Formula: C₅₉H₉₈N₁₈O₂₂
Relative Molecular Mass: 1411.54
CAS#: 823814-33-1
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cardiovascular System & Diseases
Details: MCP-1 (65-76) (human) inhibits the action of MCP-1-stimulated
monocyte migration and lipopolysaccharide (LPS)-induced
recruitment of monocytes and granulocytes. Since
MCP-1-mediated chemotaxis has been implicated in the
atherosclerotic plaque ""destabilization"" and the subsequent
acute coronary syndrome, this fragment may represent a new
class of anti-inflammatory drugs for cardiology.
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